1lyv
From Proteopedia
(Difference between revisions)
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<StructureSection load='1lyv' size='340' side='right'caption='[[1lyv]], [[Resolution|resolution]] 1.36Å' scene=''> | <StructureSection load='1lyv' size='340' side='right'caption='[[1lyv]], [[Resolution|resolution]] 1.36Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[1lyv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1lyv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LYV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LYV FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.363Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lyv OCA], [https://pdbe.org/1lyv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lyv RCSB], [https://www.ebi.ac.uk/pdbsum/1lyv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lyv ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lyv OCA], [https://pdbe.org/1lyv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lyv RCSB], [https://www.ebi.ac.uk/pdbsum/1lyv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lyv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
- | + | [https://www.uniprot.org/uniprot/YOPH_YEREN YOPH_YEREN] Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: Bacterium enterocoliticum schleifstein and coleman 1939]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: | + | [[Category: Yersinia enterocolitica]] |
- | [[Category: Cherry | + | [[Category: Cherry S]] |
- | [[Category: Evdokimov | + | [[Category: Evdokimov AG]] |
- | [[Category: Routzahn | + | [[Category: Routzahn K]] |
- | [[Category: Tropea | + | [[Category: Tropea J]] |
- | [[Category: Waugh | + | [[Category: Waugh DS]] |
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Current revision
High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant in complex with phosphate.
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