1odd

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Current revision (08:01, 14 February 2024) (edit) (undo)
 
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<StructureSection load='1odd' size='340' side='right'caption='[[1odd]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1odd' size='340' side='right'caption='[[1odd]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1odd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ODD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1odd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ODD FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1odd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1odd OCA], [https://pdbe.org/1odd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1odd RCSB], [https://www.ebi.ac.uk/pdbsum/1odd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1odd ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1odd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1odd OCA], [https://pdbe.org/1odd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1odd RCSB], [https://www.ebi.ac.uk/pdbsum/1odd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1odd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/OMPR_ECOLI OMPR_ECOLI]] The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the OmpR protein. As a multimer, it turns on the expression of the ompC gene; as a monomer, it turns on the expression of the ompF gene.
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[https://www.uniprot.org/uniprot/OMPR_ECOLI OMPR_ECOLI] The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the OmpR protein. As a multimer, it turns on the expression of the ompC gene; as a monomer, it turns on the expression of the ompF gene.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1odd ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1odd ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
 
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== Publication Abstract from PubMed ==
 
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The C-terminal DNA-binding domain of OmpR, a positive regulator involved in osmoregulation expression of the ompF and ompC genes in Escherichia coli, has a helix-turn-helix variant motif. The 'turn' region, consisting of 11 residues, forms an RNA polymerase contact site.
 
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Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site.,Kondo H, Nakagawa A, Nishihira J, Nishimura Y, Mizuno T, Tanaka I Nat Struct Biol. 1997 Jan;4(1):28-31. PMID:8989318<ref>PMID:8989318</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 1odd" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kondou, H]]
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[[Category: Kondou H]]
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[[Category: Nakagawa, A]]
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[[Category: Nakagawa A]]
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[[Category: Tanaka, I]]
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[[Category: Tanaka I]]
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[[Category: Dna binding domain]]
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[[Category: Gene regulatory protein]]
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[[Category: Positive response regulator]]
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Current revision

OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI

PDB ID 1odd

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