1r31
From Proteopedia
(Difference between revisions)
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<StructureSection load='1r31' size='340' side='right'caption='[[1r31]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='1r31' size='340' side='right'caption='[[1r31]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1r31]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1r31]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R31 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R31 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r31 OCA], [https://pdbe.org/1r31 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r31 RCSB], [https://www.ebi.ac.uk/pdbsum/1r31 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r31 ProSAT]</span></td></tr> | |
| - | < | + | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Pseudomonas mevalonii]] | ||
| - | [[Category: Hydroxymethylglutaryl-CoA reductase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Burgner | + | [[Category: Pseudomonas mevalonii]] |
| - | [[Category: Lawrence | + | [[Category: Burgner JW]] |
| - | [[Category: Rodwell | + | [[Category: Lawrence CM]] |
| - | [[Category: Stauffacher | + | [[Category: Rodwell VW]] |
| - | [[Category: Steussy | + | [[Category: Stauffacher CV]] |
| - | [[Category: Tabernero | + | [[Category: Steussy CN]] |
| - | [[Category: Watson | + | [[Category: Tabernero L]] |
| - | + | [[Category: Watson JM]] | |
| - | + | ||
Current revision
HMG-CoA reductase from Pseudomonas mevalonii complexed with HMG-CoA
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