1t6s
From Proteopedia
(Difference between revisions)
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<StructureSection load='1t6s' size='340' side='right'caption='[[1t6s]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='1t6s' size='340' side='right'caption='[[1t6s]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1t6s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1t6s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlorobaculum_tepidum_TLS Chlorobaculum tepidum TLS]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T6S FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t6s OCA], [https://pdbe.org/1t6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t6s RCSB], [https://www.ebi.ac.uk/pdbsum/1t6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t6s ProSAT], [https://www.topsan.org/Proteins/BSGC/1t6s TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t6s OCA], [https://pdbe.org/1t6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t6s RCSB], [https://www.ebi.ac.uk/pdbsum/1t6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t6s ProSAT], [https://www.topsan.org/Proteins/BSGC/1t6s TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/Q8KF54_CHLTE Q8KF54_CHLTE] Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t6s ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t6s ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins. | ||
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| - | Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning.,Kim JS, Shin DH, Pufan R, Huang C, Yokota H, Kim R, Kim SH Proteins. 2006 Feb 1;62(2):322-8. PMID:16294331<ref>PMID:16294331</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1t6s" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Chlorobaculum tepidum TLS]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Kim JS]] | |
| - | [[Category: Kim | + | [[Category: Kim R]] |
| - | [[Category: Kim | + | [[Category: Kim SH]] |
| - | [[Category: Kim | + | [[Category: Shin DH]] |
| - | [[Category: Shin | + | |
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Current revision
Crystal structure of a conserved hypothetical protein from Chlorobium tepidum
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