1tbu

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Current revision (08:38, 14 February 2024) (edit) (undo)
 
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<StructureSection load='1tbu' size='340' side='right'caption='[[1tbu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1tbu' size='340' side='right'caption='[[1tbu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1tbu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TBU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1TBU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1tbu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TBU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1c8u|1c8u]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTE1, TES1, YJR019C, J1456 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tbu OCA], [https://pdbe.org/1tbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tbu RCSB], [https://www.ebi.ac.uk/pdbsum/1tbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tbu ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Palmitoyl-CoA_hydrolase Palmitoyl-CoA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.2 3.1.2.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1tbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tbu OCA], [http://pdbe.org/1tbu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tbu RCSB], [http://www.ebi.ac.uk/pdbsum/1tbu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tbu ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PTE1_YEAST PTE1_YEAST]] Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.
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[https://www.uniprot.org/uniprot/PTE1_YEAST PTE1_YEAST] Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Palmitoyl-CoA hydrolase]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Derewenda, U]]
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[[Category: Derewenda U]]
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[[Category: Derewenda, Z S]]
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[[Category: Derewenda ZS]]
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[[Category: Devedjiev, Y D]]
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[[Category: Devedjiev YD]]
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[[Category: Li, J]]
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[[Category: Li J]]
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[[Category: Domain swapping]]
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[[Category: Hydrolase]]
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[[Category: Iodine soak]]
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[[Category: Sira]]
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[[Category: X-ray structure]]
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[[Category: Yeast peroxisomal thioesterase]]
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Current revision

Crystal structure of N-terminal domain of yeast peroxisomal thioesterase-1

PDB ID 1tbu

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