1xpp

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Current revision (08:52, 14 February 2024) (edit) (undo)
 
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<StructureSection load='1xpp' size='340' side='right'caption='[[1xpp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='1xpp' size='340' side='right'caption='[[1xpp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xpp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XPP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xpp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XPP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rpoL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 "Thermoplasma acidophila" (sic) Darland et al. 1970])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpp OCA], [https://pdbe.org/1xpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpp RCSB], [https://www.ebi.ac.uk/pdbsum/1xpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpp ProSAT], [https://www.topsan.org/Proteins/MCSG/1xpp TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpp OCA], [http://pdbe.org/1xpp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xpp RCSB], [http://www.ebi.ac.uk/pdbsum/1xpp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpp ProSAT], [http://www.topsan.org/Proteins/MCSG/1xpp TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RPOL_THEAC RPOL_THEAC]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).
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[https://www.uniprot.org/uniprot/RPO11_THEAC RPO11_THEAC] DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00261]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA-directed RNA polymerase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Edwards, A]]
 
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[[Category: Evdokimova, E]]
 
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[[Category: Joachimiak, A]]
 
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[[Category: Kim, Y]]
 
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[[Category: Structural genomic]]
 
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[[Category: Savchenko, A]]
 
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[[Category: Dna-directed rna polymerase]]
 
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[[Category: Mcsg]]
 
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[[Category: PSI, Protein structure initiative]]
 
[[Category: Thermoplasma acidophilum]]
[[Category: Thermoplasma acidophilum]]
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[[Category: Transferase]]
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[[Category: Edwards A]]
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[[Category: Evdokimova E]]
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[[Category: Joachimiak A]]
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[[Category: Kim Y]]
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[[Category: Savchenko A]]

Current revision

Crystal Structure of TA1416,DNA-directed RNA polymerase subunit L, from Thermoplasma acidophilum

PDB ID 1xpp

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