244d
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=244d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=244d OCA], [https://pdbe.org/244d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=244d RCSB], [https://www.ebi.ac.uk/pdbsum/244d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=244d ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=244d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=244d OCA], [https://pdbe.org/244d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=244d RCSB], [https://www.ebi.ac.uk/pdbsum/244d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=244d ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | Repeat tracts of guanine bases found in DNA and RNA can form tetraplex structures in the presence of a variety of monovalent cations. Evidence suggests that guanine tetraplexes assume important functions within chromosomal telomeres, immunoglobulin switch regions, and the human immunodeficiency virus genome. The structure of a parallel-stranded tetraplex formed by the hexanucleotide d(TG4T) and stabilized by sodium cations was determined by x-ray crystallography to 1.2 angstroms resolution. Sharply resolved sodium cations were found between and within planes of hydrogen-bonded guanine quartets, and an ordered groove hydration was observed. Distinct intra- and intermolecular stacking arrangements were adopted by the guanine quartets. Thymine bases were exclusively involved in making extensive lattice contacts. | ||
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| - | The high-resolution crystal structure of a parallel-stranded guanine tetraplex.,Laughlan G, Murchie AI, Norman DG, Moore MH, Moody PC, Lilley DM, Luisi B Science. 1994 Jul 22;265(5171):520-4. PMID:8036494<ref>PMID:8036494</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 244d" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
THE HIGH-RESOLUTION CRYSTAL STRUCTURE OF A PARALLEL-STRANDED GUANINE TETRAPLEX
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Categories: Large Structures | Laughlan G | Lilley DMJ | Luisi B | Moody PCE | Moore MH | Murchie AIH | Norman DG
