2an1
From Proteopedia
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<StructureSection load='2an1' size='340' side='right'caption='[[2an1]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2an1' size='340' side='right'caption='[[2an1]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2an1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2an1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AN1 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2an1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2an1 OCA], [https://pdbe.org/2an1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2an1 RCSB], [https://www.ebi.ac.uk/pdbsum/2an1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2an1 ProSAT], [https://www.topsan.org/Proteins/MCSG/2an1 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2an1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2an1 OCA], [https://pdbe.org/2an1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2an1 RCSB], [https://www.ebi.ac.uk/pdbsum/2an1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2an1 ProSAT], [https://www.topsan.org/Proteins/MCSG/2an1 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NADK_SALTY NADK_SALTY] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates as a source of phosphorus. NADH can not replace NAD as a substrate.[HAMAP-Rule:MF_00361]<ref>PMID:16682646</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] |
| - | [[Category: Collart | + | [[Category: Collart F]] |
| - | [[Category: Holzle | + | [[Category: Holzle D]] |
| - | [[Category: Joachimiak | + | [[Category: Joachimiak A]] |
| - | + | [[Category: Zhang R]] | |
| - | [[Category: Zhang | + | [[Category: Zhou M]] |
| - | [[Category: Zhou | + | |
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Current revision
Structural Genomics, The crystal structure of a putative kinase from Salmonella typhimurim LT2
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