2f0f

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Current revision (09:20, 14 February 2024) (edit) (undo)
 
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<StructureSection load='2f0f' size='340' side='right'caption='[[2f0f]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='2f0f' size='340' side='right'caption='[[2f0f]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2f0f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2f0f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0F FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ey0|1ey0]], [[2exz|2exz]], [[2ey1|2ey1]], [[2ey2|2ey2]], [[2ey5|2ey5]], [[2ey6|2ey6]], [[2eyf|2eyf]], [[2eyh|2eyh]], [[2eyj|2eyj]], [[2eyl|2eyl]], [[2eym|2eym]], [[2eyo|2eyo]], [[2eyp|2eyp]], [[2f0d|2f0d]], [[2f0e|2f0e]], [[2f0g|2f0g]], [[2f0h|2f0h]], [[2f0i|2f0i]], [[2f0j|2f0j]], [[2f0k|2f0k]], [[2f0l|2f0l]], [[2f0m|2f0m]], [[2f0n|2f0n]], [[2f0o|2f0o]], [[2f0p|2f0p]], [[2f0q|2f0q]], [[2f0s|2f0s]], [[2f0t|2f0t]], [[2f0u|2f0u]], [[2f0v|2f0v]], [[2f0w|2f0w]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0f OCA], [https://pdbe.org/2f0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0f RCSB], [https://www.ebi.ac.uk/pdbsum/2f0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0f ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0f OCA], [https://pdbe.org/2f0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0f RCSB], [https://www.ebi.ac.uk/pdbsum/2f0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
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[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Micrococcal nuclease]]
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[[Category: Staphylococcus aureus]]
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[[Category: Lu, J Z]]
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[[Category: Lu JZ]]
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[[Category: Sakon, J]]
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[[Category: Sakon J]]
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[[Category: Stites, W E]]
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[[Category: Stites WE]]
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[[Category: Calcium]]
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[[Category: Dna hydrolase]]
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[[Category: Endonuclease]]
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[[Category: Hydrolase]]
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[[Category: Rna hydrolase]]
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[[Category: Signal]]
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Current revision

Crystal structure of Staphylococcal nuclease mutant L25I

PDB ID 2f0f

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