2fgt
From Proteopedia
(Difference between revisions)
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<StructureSection load='2fgt' size='340' side='right'caption='[[2fgt]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2fgt' size='340' side='right'caption='[[2fgt]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2fgt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2fgt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FGT FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fgt OCA], [https://pdbe.org/2fgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fgt RCSB], [https://www.ebi.ac.uk/pdbsum/2fgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fgt ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fgt OCA], [https://pdbe.org/2fgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fgt RCSB], [https://www.ebi.ac.uk/pdbsum/2fgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fgt ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/YYCH_BACSU YYCH_BACSU] Together with YycI, regulates the activity of the two-component system YycF/YycG.<ref>PMID:17307850</ref> <ref>PMID:18408157</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fgt ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fgt ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The Bacillus subtilis YycFG two-component signal transduction system is essential for cell viability, and the YycH protein is part of the regulatory circuit that controls its activity. The crystal structure of YycH was solved by two-wavelength selenium anomalous dispersion data, and was refined using 2.3 A data to an R-factor of 25.2%. The molecule is made up of three domains, and has a novel three-dimensional structure. The N-terminal domain features a calcium binding site and the central domain contains two conserved loop regions. | ||
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| - | The crystal structure of YycH involved in the regulation of the essential YycFG two-component system in Bacillus subtilis reveals a novel tertiary structure.,Szurmant H, Zhao H, Mohan MA, Hoch JA, Varughese KI Protein Sci. 2006 Apr;15(4):929-34. PMID:16600972<ref>PMID:16600972</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 2fgt" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Bacillus | + | [[Category: Bacillus subtilis]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: James | + | [[Category: James HA]] |
| - | [[Category: Mohan | + | [[Category: Mohan MA]] |
| - | [[Category: Szurmant | + | [[Category: Szurmant H]] |
| - | [[Category: Varughese | + | [[Category: Varughese KI]] |
| - | [[Category: Zhao | + | [[Category: Zhao H]] |
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Current revision
Crystal Structure of YycH from Bacillus subtilis
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