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8dt6
From Proteopedia
(Difference between revisions)
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==Crystal Structure of DNA Polymerase III beta subunit from Elizabethkingia anophelis== | ==Crystal Structure of DNA Polymerase III beta subunit from Elizabethkingia anophelis== | ||
| - | <StructureSection load='8dt6' size='340' side='right'caption='[[8dt6]]' scene=''> | + | <StructureSection load='8dt6' size='340' side='right'caption='[[8dt6]], [[Resolution|resolution]] 2.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DT6 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[8dt6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Elizabethkingia_anophelis_NUHP1 Elizabethkingia anophelis NUHP1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DT6 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dt6 OCA], [https://pdbe.org/8dt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dt6 RCSB], [https://www.ebi.ac.uk/pdbsum/8dt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dt6 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dt6 OCA], [https://pdbe.org/8dt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dt6 RCSB], [https://www.ebi.ac.uk/pdbsum/8dt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dt6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A077EHW1_9FLAO A0A077EHW1_9FLAO] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Elizabethkingia anophelis NUHP1]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
Current revision
Crystal Structure of DNA Polymerase III beta subunit from Elizabethkingia anophelis
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