8dt6

<StructureSection load='8dt6' size='340' side='right'caption='[[8dt6]], [[Resolution|resolution]] 2.35&Aring;' scene=''>

<table><tr><td colspan='2'>[[8dt6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Elizabethkingia_anophelis_NUHP1 Elizabethkingia anophelis NUHP1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DT6 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dt6 OCA], [https://pdbe.org/8dt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dt6 RCSB], [https://www.ebi.ac.uk/pdbsum/8dt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dt6 ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/A0A077EHW1_9FLAO A0A077EHW1_9FLAO] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]

==See Also==

*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]

[[Category: Elizabethkingia anophelis NUHP1]]