3n3y

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Current revision (09:58, 14 February 2024) (edit) (undo)
 
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<StructureSection load='3n3y' size='340' side='right'caption='[[3n3y]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
<StructureSection load='3n3y' size='340' side='right'caption='[[3n3y]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3n3y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_(strain_ss1) Helicobacter pylori (strain ss1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N3Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3n3y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_SS1 Helicobacter pylori SS1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N3Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.307&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ThyX ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=102617 Helicobacter pylori (strain SS1)])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thymidylate_synthase_(FAD) Thymidylate synthase (FAD)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.148 2.1.1.148] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n3y OCA], [https://pdbe.org/3n3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n3y RCSB], [https://www.ebi.ac.uk/pdbsum/3n3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n3y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n3y OCA], [https://pdbe.org/3n3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n3y RCSB], [https://www.ebi.ac.uk/pdbsum/3n3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n3y ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q5UVJ4_HELPX Q5UVJ4_HELPX]] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.[HAMAP-Rule:MF_01408]
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[https://www.uniprot.org/uniprot/Q5UVJ4_HELPX Q5UVJ4_HELPX] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.[HAMAP-Rule:MF_01408]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Helicobacter pylori SS1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chen, J]]
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[[Category: Chen J]]
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[[Category: Chen, L]]
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[[Category: Chen L]]
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[[Category: Jiang, H]]
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[[Category: Jiang H]]
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[[Category: Shen, X]]
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[[Category: Shen X]]
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[[Category: Wang, K]]
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[[Category: Wang K]]
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[[Category: Wang, Q]]
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[[Category: Wang Q]]
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[[Category: Helicobacter pylori]]
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[[Category: Thymidylate synthase thyx]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Thymidylate Synthase X (ThyX) from Helicobacter pylori with FAD and dUMP at 2.31A resolution

PDB ID 3n3y

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