8ceg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8ceg is ON HOLD until Paper Publication
+
==BAR domain protein FAM92A1 essential for mitochondrial membrane remodeling==
-
 
+
<StructureSection load='8ceg' size='340' side='right'caption='[[8ceg]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
-
Authors: Kajander, T., Fudo, S., Yan, Z., Zhao, H.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8ceg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CEG FirstGlance]. <br>
-
Description: BAR domain protein FAM92A1 essential for mitochondrial membrane remodeling
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ceg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ceg OCA], [https://pdbe.org/8ceg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ceg RCSB], [https://www.ebi.ac.uk/pdbsum/8ceg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ceg ProSAT]</span></td></tr>
-
[[Category: Kajander, T]]
+
</table>
-
[[Category: Fudo, S]]
+
== Disease ==
-
[[Category: Zhao, H]]
+
[https://www.uniprot.org/uniprot/CBAR1_HUMAN CBAR1_HUMAN] Postaxial polydactyly type A. The disease may be caused by variants affecting the gene represented in this entry.
-
[[Category: Yan, Z]]
+
== Function ==
 +
[https://www.uniprot.org/uniprot/CBAR1_HUMAN CBAR1_HUMAN] Acts as a positive regulator of ciliary hedgehog signaling (By similarity). Probable regulator of ciliogenesis involved in limb morphogenesis (PubMed:27528616, PubMed:30395363). In cooperation with CBY1 it is involved in the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis (PubMed:27528616, PubMed:30395363). Plays an important role in the mitochondrial function and is essential for maintaining mitochondrial morphology and inner membrane ultrastructure (PubMed:30404948). In vitro, can generate membrane curvature through preferential interaction with negatively charged phospholipids such as phosphatidylinositol 4,5-bisphosphate and cardiolipin and hence orchestrate cristae shape (PubMed:30404948).[UniProtKB:Q8BP22]<ref>PMID:27528616</ref> <ref>PMID:30395363</ref> <ref>PMID:30404948</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Fudo S]]
 +
[[Category: Kajander T]]
 +
[[Category: Yan Z]]
 +
[[Category: Zhao H]]

Revision as of 08:52, 21 February 2024

BAR domain protein FAM92A1 essential for mitochondrial membrane remodeling

PDB ID 8ceg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8ceg"
Personal tools