2qlt

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Current revision (09:16, 21 February 2024) (edit) (undo)
 
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<StructureSection load='2qlt' size='340' side='right'caption='[[2qlt]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2qlt' size='340' side='right'caption='[[2qlt]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qlt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QLT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qlt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QLT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPP1, RHR2, YIL053W ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qlt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qlt OCA], [https://pdbe.org/2qlt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qlt RCSB], [https://www.ebi.ac.uk/pdbsum/2qlt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qlt ProSAT], [https://www.topsan.org/Proteins/MCSG/2qlt TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qlt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qlt OCA], [https://pdbe.org/2qlt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qlt RCSB], [https://www.ebi.ac.uk/pdbsum/2qlt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qlt ProSAT], [https://www.topsan.org/Proteins/MCSG/2qlt TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/GPP1_YEAST GPP1_YEAST]] Major isoform of glycerol-1-phosphate phosphohydrolase involved in glycerol biosynthesis. Plays a role in osmoadaptation and required for adaptation to anaerobic conditions.<ref>PMID:8662716</ref> <ref>PMID:11058591</ref> <ref>PMID:15113568</ref> <ref>PMID:16358322</ref> <ref>PMID:18438874</ref>
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[https://www.uniprot.org/uniprot/GPP1_YEAST GPP1_YEAST] Major isoform of glycerol-1-phosphate phosphohydrolase involved in glycerol biosynthesis. Plays a role in osmoadaptation and required for adaptation to anaerobic conditions.<ref>PMID:8662716</ref> <ref>PMID:11058591</ref> <ref>PMID:15113568</ref> <ref>PMID:16358322</ref> <ref>PMID:18438874</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Edwards, A]]
 
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[[Category: Evdokimova, E]]
 
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[[Category: Joachimiak, A]]
 
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[[Category: Kudritska, M]]
 
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[[Category: Structural genomic]]
 
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[[Category: Savchenko, A]]
 
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[[Category: Tan, K]]
 
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[[Category: Apc7326]]
 
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[[Category: Dl-glycerol-3-phosphatase isoform]]
 
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[[Category: Hydrolase]]
 
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[[Category: Mcsg]]
 
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[[Category: PSI, Protein structure initiative]]
 
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[[Category: Rhr2p]]
 
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Edwards A]]
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[[Category: Evdokimova E]]
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[[Category: Joachimiak A]]
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[[Category: Kudritska M]]
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[[Category: Savchenko A]]
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[[Category: Tan K]]

Current revision

Crystal structure of an isoform of DL-glycerol-3-phosphatase, Rhr2p, from Saccharomyces cerevisiae

PDB ID 2qlt

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OCA

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