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2r0b
From Proteopedia
(Difference between revisions)
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==Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein== | ==Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein== | ||
| - | <StructureSection load='2r0b' size='340' side='right'caption='[[2r0b]]' scene=''> | + | <StructureSection load='2r0b' size='340' side='right'caption='[[2r0b]], [[Resolution|resolution]] 1.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R0B FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2r0b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R0B FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r0b OCA], [https://pdbe.org/2r0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r0b RCSB], [https://www.ebi.ac.uk/pdbsum/2r0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r0b ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2r0b TOPSAN]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r0b OCA], [https://pdbe.org/2r0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r0b RCSB], [https://www.ebi.ac.uk/pdbsum/2r0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r0b ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2r0b TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/STYX_HUMAN STYX_HUMAN] Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). Seems to play a role in spermiogenesis (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Almo SC]] | [[Category: Almo SC]] | ||
Current revision
Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein
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Categories: Homo sapiens | Large Structures | Almo SC | Bain KT | Bonanno JB | Burley SK | Freeman J | Iizuka M | Romero R | Sauder JM | Smith D | Wasserman S
