3cz3
From Proteopedia
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<StructureSection load='3cz3' size='340' side='right'caption='[[3cz3]], [[Resolution|resolution]] 3.23Å' scene=''> | <StructureSection load='3cz3' size='340' side='right'caption='[[3cz3]], [[Resolution|resolution]] 3.23Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3cz3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3cz3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_aspermy_virus Tomato aspermy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CZ3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.23Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz3 OCA], [https://pdbe.org/3cz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cz3 RCSB], [https://www.ebi.ac.uk/pdbsum/3cz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cz3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz3 OCA], [https://pdbe.org/3cz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cz3 RCSB], [https://www.ebi.ac.uk/pdbsum/3cz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cz3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/2B_TAV 2B_TAV] Acts as suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Forms a homodimer to measure siRNA duplex in a length-preferencemode. Binds to both siRNA duplexes (19bp) and long siRNA duplexes (30bp).<ref>PMID:10329615</ref> <ref>PMID:8291242</ref> <ref>PMID:9010309</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Chrysanthemum aspermy virus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Tomato aspermy virus]] |
| - | [[Category: | + | [[Category: Ding SW]] |
| - | [[Category: | + | [[Category: Li F]] |
| - | [[Category: | + | [[Category: Ma JB]] |
| - | [[Category: | + | [[Category: Patel DJ]] |
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Current revision
Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA
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