3d0o

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Current revision (09:39, 21 February 2024) (edit) (undo)
 
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<StructureSection load='3d0o' size='340' side='right'caption='[[3d0o]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3d0o' size='340' side='right'caption='[[3d0o]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3d0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D0O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3d0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D0O FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ldh1, SACOL0222 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d0o OCA], [https://pdbe.org/3d0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d0o RCSB], [https://www.ebi.ac.uk/pdbsum/3d0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d0o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d0o OCA], [https://pdbe.org/3d0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d0o RCSB], [https://www.ebi.ac.uk/pdbsum/3d0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d0o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC]] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>
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[https://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: L-lactate dehydrogenase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staac]]
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[[Category: Staphylococcus aureus subsp. aureus COL]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Gutierrez, J A]]
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[[Category: Gutierrez JA]]
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[[Category: Ho, M]]
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[[Category: Ho M]]
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[[Category: Schramm, V L]]
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[[Category: Schramm VL]]
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[[Category: Cytoplasm]]
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[[Category: Glycolysis]]
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[[Category: Lactate dehydrogenase]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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[[Category: Phosphoprotein]]
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[[Category: Staphylococcus aureus]]
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Current revision

Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus

PDB ID 3d0o

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