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3dal

From Proteopedia

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Current revision (09:40, 21 February 2024) (edit) (undo)
 
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<StructureSection load='3dal' size='340' side='right'caption='[[3dal]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='3dal' size='340' side='right'caption='[[3dal]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3dal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DAL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3dal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DAL FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRDM1, BLIMP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dal OCA], [https://pdbe.org/3dal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dal RCSB], [https://www.ebi.ac.uk/pdbsum/3dal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dal ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dal OCA], [https://pdbe.org/3dal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dal RCSB], [https://www.ebi.ac.uk/pdbsum/3dal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dal ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PRDM1_HUMAN PRDM1_HUMAN]] Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.
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[https://www.uniprot.org/uniprot/PRDM1_HUMAN PRDM1_HUMAN] Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Amaya, M F]]
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[[Category: Amaya MF]]
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[[Category: Antoshenko, T]]
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[[Category: Antoshenko T]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Dong, A]]
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[[Category: Dong A]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Loppnau, P]]
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[[Category: Loppnau P]]
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[[Category: Min, J]]
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[[Category: Min J]]
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[[Category: Plotnikov, A N]]
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[[Category: Plotnikov AN]]
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[[Category: Structural genomic]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Wu H]]
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[[Category: Wu, H]]
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[[Category: Zeng H]]
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[[Category: Zeng, H]]
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[[Category: Dna binding protein]]
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[[Category: Dna-binding]]
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[[Category: Metal-binding]]
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[[Category: Methyltransferase]]
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[[Category: Nucleus]]
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[[Category: Polymorphism]]
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[[Category: Prdm1]]
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[[Category: Repressor]]
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[[Category: Sgc]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transferase]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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Current revision

Methyltransferase domain of human PR domain-containing protein 1

PDB ID 3dal

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OCA

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