3fn8

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Current revision (09:49, 21 February 2024) (edit) (undo)
 
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<StructureSection load='3fn8' size='340' side='right'caption='[[3fn8]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='3fn8' size='340' side='right'caption='[[3fn8]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3fn8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FN8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3fn8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FN8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3f0p|3f0p]], [[1s6l|1s6l]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">merB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alkylmercury_lyase Alkylmercury lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.2 4.99.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fn8 OCA], [https://pdbe.org/3fn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fn8 RCSB], [https://www.ebi.ac.uk/pdbsum/3fn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fn8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fn8 OCA], [https://pdbe.org/3fn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fn8 RCSB], [https://www.ebi.ac.uk/pdbsum/3fn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fn8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX]] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).
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[https://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Alkylmercury lyase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cagle, C]]
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[[Category: Cagle C]]
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[[Category: Momany, C]]
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[[Category: Momany C]]
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[[Category: Summers, A]]
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[[Category: Summers A]]
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[[Category: Teske, J]]
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[[Category: Teske J]]
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[[Category: Lyase]]
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[[Category: Mercuric resistance]]
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[[Category: Mercury]]
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[[Category: Winged-helix]]
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Current revision

Crystal Structure of MerB complexed with mercury

PDB ID 3fn8

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