3kk5

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Current revision (10:17, 21 February 2024) (edit) (undo)
 
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<SX load='3kk5' size='340' side='right' viewer='molstar' caption='[[3kk5]], [[Resolution|resolution]] 10.60&Aring;' scene=''>
<SX load='3kk5' size='340' side='right' viewer='molstar' caption='[[3kk5]], [[Resolution|resolution]] 10.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3kk5]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Acanthamoeba_polyphaga Acanthamoeba polyphaga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KK5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3KK5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3kk5]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_polyphaga Acanthamoeba polyphaga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KK5 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m3y|1m3y]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3kk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kk5 OCA], [http://pdbe.org/3kk5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kk5 RCSB], [http://www.ebi.ac.uk/pdbsum/3kk5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kk5 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kk5 OCA], [https://pdbe.org/3kk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kk5 RCSB], [https://www.ebi.ac.uk/pdbsum/3kk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kk5 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MCP_PBCV1 MCP_PBCV1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kk5 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kk5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
 
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== Publication Abstract from PubMed ==
 
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The virophage Sputnik is a satellite virus of the giant mimivirus and is the only satellite virus reported to date whose propagation adversely affects its host virus' production. Genome sequence analysis showed that Sputnik has genes related to viruses infecting all three domains of life. Here, we report structural studies of Sputnik, which show that it is about 740 A in diameter, has a T=27 icosahedral capsid, and has a lipid membrane inside the protein shell. Structural analyses suggest that the major capsid protein of Sputnik is likely to have a double jelly-roll fold, although sequence alignments do not show any detectable similarity with other viral double jelly-roll capsid proteins. Hence, the origin of Sputnik's capsid might have been derived from other viruses prior to its association with mimivirus.
 
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Structural studies of the Sputnik virophage.,Sun S, La Scola B, Bowman VD, Ryan CM, Whitelegge JP, Raoult D, Rossmann MG J Virol. 2010 Jan;84(2):894-7. Epub 2009 Nov 4. PMID:19889775<ref>PMID:19889775</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 3kk5" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</SX>
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[[Category: Acanthamoeba polyphaga]]
[[Category: Acanthamoeba polyphaga]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Rossmann, M G]]
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[[Category: Rossmann MG]]
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[[Category: Sun, S]]
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[[Category: Sun S]]
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[[Category: Capsid protein]]
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[[Category: Double jellyroll]]
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[[Category: Icosahedral virus]]
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[[Category: Late protein]]
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[[Category: Virion]]
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[[Category: Virus]]
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Current revision

Crystal structure of PBCV-1 VP54 fitted into a cryo-EM reconstruction of the virophage Sputnik

3kk5, resolution 10.60Å

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