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3kke

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Current revision (10:17, 21 February 2024) (edit) (undo)
 
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==Crystal structure of a LacI family transcriptional regulator from Mycobacterium smegmatis==
==Crystal structure of a LacI family transcriptional regulator from Mycobacterium smegmatis==
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<StructureSection load='3kke' size='340' side='right' caption='[[3kke]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3kke' size='340' side='right'caption='[[3kke]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3kke]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KKE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KKE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3kke]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KKE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSMEG_0491 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=246196 MYCS2])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kke OCA], [http://pdbe.org/3kke PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kke RCSB], [http://www.ebi.ac.uk/pdbsum/3kke PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kke ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kke OCA], [https://pdbe.org/3kke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kke RCSB], [https://www.ebi.ac.uk/pdbsum/3kke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kke ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0QPR6_MYCS2 A0QPR6_MYCS2]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kk/3kke_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kk/3kke_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kke ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kke ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycs2]]
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[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Mycolicibacterium smegmatis MC2 155]]
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[[Category: Bain, K T]]
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[[Category: Almo SC]]
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[[Category: Bonanno, J B]]
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[[Category: Bain KT]]
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[[Category: Burley, S K]]
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[[Category: Bonanno JB]]
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[[Category: Do, J]]
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[[Category: Burley SK]]
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[[Category: Structural genomic]]
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[[Category: Do J]]
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[[Category: Ozyurt, S]]
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[[Category: Ozyurt S]]
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[[Category: Rutter, M]]
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[[Category: Rutter M]]
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[[Category: Sauder, J M]]
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[[Category: Sauder JM]]
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[[Category: Wasserman, S]]
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[[Category: Wasserman S]]
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[[Category: Dna-binding]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcription regulator]]
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Current revision

Crystal structure of a LacI family transcriptional regulator from Mycobacterium smegmatis

PDB ID 3kke

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