3ois

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:34, 21 February 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3ois' size='340' side='right'caption='[[3ois]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='3ois' size='340' side='right'caption='[[3ois]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3ois]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35879 Atcc 35879]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OIS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3ois]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Xylella_fastidiosa Xylella fastidiosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OIS FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">XF_0156 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2371 ATCC 35879])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ois FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ois OCA], [https://pdbe.org/3ois PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ois RCSB], [https://www.ebi.ac.uk/pdbsum/3ois PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ois ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ois FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ois OCA], [https://pdbe.org/3ois PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ois RCSB], [https://www.ebi.ac.uk/pdbsum/3ois PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ois ProSAT]</span></td></tr>
</table>
</table>
-
<div style="background-color:#fffaf0;">
+
== Function ==
-
== Publication Abstract from PubMed ==
+
[https://www.uniprot.org/uniprot/Q9PGZ0_XYLFA Q9PGZ0_XYLFA]
-
Xylella fastidiosa is responsible for a wide range of economically important plant diseases. We report here the crystal structure and kinetic data of Xylellain, the first cysteine protease characterized from the genome of the pathogenic X. fastidiosa strain 9a5c. Xylellain has a papain-family fold, and part of the N-terminal sequence blocks the enzyme active site, thereby mediating protein activity. One novel feature identified in the structure is the presence of a ribonucleotide bound outside the active site. We show that this ribonucleotide plays an important regulatory role in Xylellain enzyme kinetics, possibly functioning as a physiological mediator. STRUCTURED SUMMARY OF PROTEIN INTERACTIONS: Xylellain and Xylellainbind by X-ray crystallography (View interaction).
+
-
 
+
-
The crystal structure of the cysteine protease Xylellain from Xylella fastidiosa reveals an intriguing activation mechanism.,Leite NR, Faro AR, Dotta MA, Faim LM, Gianotti A, Silva FH, Oliva G, Thiemann OH FEBS Lett. 2013 Feb 14;587(4):339-44. doi: 10.1016/j.febslet.2013.01.009. Epub, 2013 Jan 17. PMID:23333295<ref>PMID:23333295</ref>
+
-
 
+
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
-
<div class="pdbe-citations 3ois" style="background-color:#fffaf0;"></div>
+
-
== References ==
+
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 35879]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Faro, A R]]
+
[[Category: Xylella fastidiosa]]
-
[[Category: Leite, N R]]
+
[[Category: Faro AR]]
-
[[Category: Oliva, G]]
+
[[Category: Leite NR]]
-
[[Category: Oliva, M A.V]]
+
[[Category: Oliva G]]
-
[[Category: Thiemann, O H]]
+
[[Category: Oliva MAV]]
-
[[Category: Alpha and beta]]
+
[[Category: Thiemann OH]]
-
[[Category: Hydrolase]]
+

Current revision

Crystal Structure Xylellain, a cysteine protease from Xylella fastidiosa

PDB ID 3ois

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ois"
Personal tools