3q1c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:45, 21 February 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3q1c' size='340' side='right'caption='[[3q1c]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='3q1c' size='340' side='right'caption='[[3q1c]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3q1c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eco27 Eco27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q1C FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3q1c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O127:H6_str._E2348/69 Escherichia coli O127:H6 str. E2348/69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q1C FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">E2348C_3970, E2348_C_3970, espG ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=574521 ECO27])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.596&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q1c OCA], [https://pdbe.org/3q1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q1c RCSB], [https://www.ebi.ac.uk/pdbsum/3q1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q1c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q1c OCA], [https://pdbe.org/3q1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q1c RCSB], [https://www.ebi.ac.uk/pdbsum/3q1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q1c ProSAT]</span></td></tr>
</table>
</table>
-
<div style="background-color:#fffaf0;">
+
== Function ==
-
== Publication Abstract from PubMed ==
+
[https://www.uniprot.org/uniprot/B7UMC8_ECO27 B7UMC8_ECO27]
-
Bacterial pathogens secrete effectors into their hosts that subvert host defenses and redirect host processes. EspG is a type three secretion effector with a disputed function that is found in enteropathogenic Escherichia coli. Here we show that EspG is structurally similar to VirA, a Shigella virulence factor; EspG has a large, conserved pocket on its surface; EspG binds directly to the amino-terminal inhibitory domain of human p21-activated kinase (PAK); and mutations to conserved residues in the surface pocket disrupt the interaction with PAK.
+
-
 
+
-
Structural and Functional Studies Indicate That the EPEC Effector, EspG, Directly Binds p21-Activated Kinase.,Germane KL, Spiller BW Biochemistry. 2011 Feb 15;50(6):917-9. Epub 2011 Jan 24. PMID:21235237<ref>PMID:21235237</ref>
+
-
 
+
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
-
<div class="pdbe-citations 3q1c" style="background-color:#fffaf0;"></div>
+
-
== References ==
+
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Eco27]]
+
[[Category: Escherichia coli O127:H6 str. E2348/69]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Germane, K L]]
+
[[Category: Germane KL]]
-
[[Category: Spiller, B W]]
+
[[Category: Spiller BW]]
-
[[Category: P21 activated kinase]]
+
-
[[Category: Pak recruitment and activation]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Vira fold]]
+
-
[[Category: Virulence factor]]
+

Current revision

Structure of EspG Protein

PDB ID 3q1c

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3q1c"
Personal tools