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3qsa

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Current revision (10:49, 21 February 2024) (edit) (undo)
 
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<StructureSection load='3qsa' size='340' side='right'caption='[[3qsa]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
<StructureSection load='3qsa' size='340' side='right'caption='[[3qsa]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qsa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QSA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qsa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QSA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene>, <scene name='pdbligand=TA7:4,4,4-TRIFLUORO-1-(4-METHOXYPHENYL)BUTANE-1,3-DIONE'>TA7</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3qqs|3qqs]], [[3qr9|3qr9]], [[3qs8|3qs8]], [[2bpq|2bpq]], [[1zvw|1zvw]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene>, <scene name='pdbligand=TA7:4,4,4-TRIFLUORO-1-(4-METHOXYPHENYL)BUTANE-1,3-DIONE'>TA7</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT2248, MTCY190.03c, trpD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsa OCA], [https://pdbe.org/3qsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qsa RCSB], [https://www.ebi.ac.uk/pdbsum/3qsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qsa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsa OCA], [https://pdbe.org/3qsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qsa RCSB], [https://www.ebi.ac.uk/pdbsum/3qsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qsa ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRPD_MYCTU TRPD_MYCTU]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anthranilate phosphoribosyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Castell, A]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Lott, J S]]
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[[Category: Castell A]]
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[[Category: Short, F L]]
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[[Category: Lott JS]]
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[[Category: Structural genomic]]
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[[Category: Short FL]]
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[[Category: Anthranilic acid]]
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[[Category: Magnesium]]
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[[Category: Magnesium binding phosphoribosyl pyrophosphate]]
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[[Category: Tbsgc]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Tryptophan]]
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Current revision

Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor TAMU-A7)

PDB ID 3qsa

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