3of5

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Current revision (11:16, 21 February 2024) (edit) (undo)
 
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<StructureSection load='3of5' size='340' side='right'caption='[[3of5]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
<StructureSection load='3of5' size='340' side='right'caption='[[3of5]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3of5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fratt Fratt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OF5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3of5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis_SCHU_S4 Francisella tularensis subsp. tularensis SCHU S4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OF5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bioD, FTT_0934c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 FRATT])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dethiobiotin_synthase Dethiobiotin synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.3 6.3.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3of5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3of5 OCA], [https://pdbe.org/3of5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3of5 RCSB], [https://www.ebi.ac.uk/pdbsum/3of5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3of5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3of5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3of5 OCA], [https://pdbe.org/3of5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3of5 RCSB], [https://www.ebi.ac.uk/pdbsum/3of5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3of5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/BIOD_FRATT BIOD_FRATT]] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.[HAMAP-Rule:MF_00336]
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[https://www.uniprot.org/uniprot/BIOD_FRATT BIOD_FRATT] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.[HAMAP-Rule:MF_00336]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dethiobiotin synthase]]
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[[Category: Francisella tularensis subsp. tularensis SCHU S4]]
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[[Category: Fratt]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Brunzelle, J S]]
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[[Category: Brunzelle JS]]
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[[Category: Structural genomic]]
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[[Category: Gordon E]]
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[[Category: Gordon, E]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A]]
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[[Category: Skarina T]]
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[[Category: Skarina, T]]
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[[Category: Csgid]]
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[[Category: Dethiobiotin synthetase]]
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[[Category: Ligase]]
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Current revision

Crystal Structure of a Dethiobiotin Synthetase from Francisella tularensis subsp. tularensis SCHU S4

PDB ID 3of5

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