1qjd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1qjd.jpg|left|200px]]
[[Image:1qjd.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1qjd |SIZE=350|CAPTION= <scene name='initialview01'>1qjd</scene>, resolution 1.80&Aring;
+
The line below this paragraph, containing "STRUCTURE_1qjd", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=SBS:Substrate+Binding+Site'>SBS</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TEO:MALATE+LIKE+INTERMEDIATE'>TEO</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1qjd| PDB=1qjd | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qjd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjd OCA], [http://www.ebi.ac.uk/pdbsum/1qjd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qjd RCSB]</span>
+
-
}}
+
'''FLAVOCYTOCHROME C3 FROM SHEWANELLA FRIGIDIMARINA'''
'''FLAVOCYTOCHROME C3 FROM SHEWANELLA FRIGIDIMARINA'''
Line 30: Line 27:
[[Category: Taylor, P.]]
[[Category: Taylor, P.]]
[[Category: Walkinshaw, M D.]]
[[Category: Walkinshaw, M D.]]
-
[[Category: fumarate reductase]]
+
[[Category: Fumarate reductase]]
-
[[Category: respiratory fumarate reductase]]
+
[[Category: Respiratory fumarate reductase]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:20:43 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:14:32 2008''
+

Revision as of 03:20, 3 May 2008

Image:1qjd.jpg

Template:STRUCTURE 1qjd

FLAVOCYTOCHROME C3 FROM SHEWANELLA FRIGIDIMARINA


Overview

The 1.8 A resolution crystal structure of the tetraheme flavocytochrome c3, Fcc3, provides the first mechanistic insight into respiratory fumarate reductases or succinate dehydrogenases. The multi-redox center, three-domain protein shows a 40 A long 'molecular wire' allowing rapid conduction of electrons through a new type of cytochrome domain onto the active site flavin, driving the reduction of fumarate to succinate. In this structure a malate-like molecule is trapped in the enzyme active site. The interactions between this molecule and the enzyme suggest a clear mechanism for fumarate reduction in which the substrate is polarized and twisted, facilitating hydride transfer from the reduced flavin and subsequent proton transfer. The enzyme active site in the oxidized form is completely buried at the interface between the flavin-binding and the clamp domains. Movement of the cytochrome and clamp domains is postulated to allow release of the product.

About this Structure

1QJD is a Single protein structure of sequence from Shewanella frigidimarina. Full crystallographic information is available from OCA.

Reference

Structural and mechanistic mapping of a unique fumarate reductase., Taylor P, Pealing SL, Reid GA, Chapman SK, Walkinshaw MD, Nat Struct Biol. 1999 Dec;6(12):1108-12. PMID:10581550 Page seeded by OCA on Sat May 3 06:20:43 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qjd"
Personal tools