8iet

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Current revision (09:36, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8iet is ON HOLD until 2025-02-22
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==Human SLC26A3 in the apo state==
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<StructureSection load='8iet' size='340' side='right'caption='[[8iet]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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Authors: Li, X.R., Chi, X.M., Zhang, Y.Y., Zhou, Q.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8iet]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IET OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IET FirstGlance]. <br>
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Description: Human SLC26A3 in the apo state
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8iet FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8iet OCA], [https://pdbe.org/8iet PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8iet RCSB], [https://www.ebi.ac.uk/pdbsum/8iet PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8iet ProSAT]</span></td></tr>
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[[Category: Zhang, Y.Y]]
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</table>
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[[Category: Li, X.R]]
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== Disease ==
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[[Category: Zhou, Q]]
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[https://www.uniprot.org/uniprot/S26A3_HUMAN S26A3_HUMAN] Congenital chloride diarrhea. The disease is caused by variants affecting the gene represented in this entry.
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[[Category: Chi, X.M]]
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== Function ==
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[https://www.uniprot.org/uniprot/S26A3_HUMAN S26A3_HUMAN] Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094). Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity).[UniProtKB:Q9WVC8]<ref>PMID:16606687</ref> <ref>PMID:19321737</ref> <ref>PMID:22159084</ref> <ref>PMID:22627094</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chi XM]]
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[[Category: Li XR]]
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[[Category: Zhang YY]]
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[[Category: Zhou Q]]

Current revision

Human SLC26A3 in the apo state

PDB ID 8iet

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OCA

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