3s8b

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Current revision (09:48, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3s8b' size='340' side='right'caption='[[3s8b]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='3s8b' size='340' side='right'caption='[[3s8b]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s8b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S8B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s8b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S8B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2cvu|2cvu]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRT7, RIR1, RNR1, Saccharomyces, SDS12, YER070W ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s8b OCA], [https://pdbe.org/3s8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s8b RCSB], [https://www.ebi.ac.uk/pdbsum/3s8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s8b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s8b OCA], [https://pdbe.org/3s8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s8b RCSB], [https://www.ebi.ac.uk/pdbsum/3s8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s8b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RIR1_YEAST RIR1_YEAST]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.<ref>PMID:11893751</ref>
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[https://www.uniprot.org/uniprot/RIR1_YEAST RIR1_YEAST] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.<ref>PMID:11893751</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Ahmad, M F]]
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[[Category: Ahmad MF]]
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[[Category: Dealwis, C D]]
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[[Category: Dealwis CD]]
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[[Category: Huang, M]]
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[[Category: Huang M]]
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[[Category: Kaushal, P S]]
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[[Category: Kaushal PS]]
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[[Category: Wan, Q]]
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[[Category: Wan Q]]
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[[Category: Wijeratna, S R]]
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[[Category: Wijeratna SR]]
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[[Category: Allostery]]
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[[Category: Dntp regulation]]
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[[Category: Oxidoreductase]]
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Current revision

Structure of Yeast Ribonucleotide Reductase 1 with AMPPNP and CDP

PDB ID 3s8b

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OCA

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