1qks

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[[Image:1qks.jpg|left|200px]]
[[Image:1qks.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1qks |SIZE=350|CAPTION= <scene name='initialview01'>1qks</scene>, resolution 1.28&Aring;
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The line below this paragraph, containing "STRUCTURE_1qks", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=C1A:The+C+Haem+Is+The+Point+Of+Electron+Entry'>C1A</scene>, <scene name='pdbsite=C1B:The+C+Haem+Is+The+Point+Of+Electron+Entry'>C1B</scene>, <scene name='pdbsite=D1A:The+D1+Haem+Is+The+Site+Of+Catalytic+Acti'>D1A</scene> and <scene name='pdbsite=D1B:The+D1+Haem+Is+The+Site+Of+Catalytic+Acti'>D1B</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=DHE:HEME+D'>DHE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1qks| PDB=1qks | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qks OCA], [http://www.ebi.ac.uk/pdbsum/1qks PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qks RCSB]</span>
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}}
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'''CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM'''
'''CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM'''
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Fulop, V.]]
[[Category: Fulop, V.]]
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[[Category: denitrification]]
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[[Category: Denitrification]]
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[[Category: electron transport]]
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[[Category: Electron transport]]
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[[Category: enzyme]]
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[[Category: Enzyme]]
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[[Category: nitrite reductase]]
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[[Category: Nitrite reductase]]
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[[Category: oxidoreductase]]
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[[Category: Oxidoreductase]]
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[[Category: periplasmic]]
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[[Category: Periplasmic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:23:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:15:07 2008''
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Revision as of 03:23, 3 May 2008

Image:1qks.jpg

Template:STRUCTURE 1qks

CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM


Overview

Cytochrome cd1-nitrite reductase is a bifunctional enzyme that catalyzes the one-electron reduction of nitrite to nitric oxide and the four-electron reduction of oxygen to water. The 1.55 A crystal structure of the dimeric enzyme from Thiosphaera pantotropha is reported here. The protein was sequenced from the X-ray structure. Each subunit contains a covalent c heme with two axial His ligands (His-17, His-69) and a unique noncovalent d1 heme ligated by Tyr-25 and His-200. The d1 heme is the mononuclear iron center where both oxygen and nitrite reduction take place. The two types of heme are located in separate domains whose arrangement suggests a mechanism requiring domain movement during catalysis.

About this Structure

1QKS is a Single protein structure of sequence from Paracoccus denitrificans. Full crystallographic information is available from OCA.

Reference

The anatomy of a bifunctional enzyme: structural basis for reduction of oxygen to water and synthesis of nitric oxide by cytochrome cd1., Fulop V, Moir JW, Ferguson SJ, Hajdu J, Cell. 1995 May 5;81(3):369-77. PMID:7736589 Page seeded by OCA on Sat May 3 06:23:45 2008

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OCA

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