3tlx

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Current revision (10:09, 1 March 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tlx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLX FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tlx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenylate_kinase Adenylate kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.3 2.7.4.3] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlx OCA], [https://pdbe.org/3tlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tlx RCSB], [https://www.ebi.ac.uk/pdbsum/3tlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlx OCA], [https://pdbe.org/3tlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tlx RCSB], [https://www.ebi.ac.uk/pdbsum/3tlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlx ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KAD1_PLAF7 KAD1_PLAF7] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (PubMed:15478799). Has very low activity with CTP, GTP, ITP and UTP and no activity with GMP, CMP, UMP or IMP in vitro (PubMed:15478799).<ref>PMID:15478799</ref>
==See Also==
==See Also==
*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenylate kinase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: Amani, M]]
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[[Category: Amani M]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Crombet, L]]
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[[Category: Crombet L]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Hui, R]]
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[[Category: Hui R]]
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[[Category: Loppnau, P]]
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[[Category: Loppnau P]]
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[[Category: Park, H]]
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[[Category: Park H]]
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[[Category: Perieteanu, A]]
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[[Category: Perieteanu A]]
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[[Category: Structural genomic]]
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[[Category: Weadge J]]
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[[Category: Weadge, J]]
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[[Category: Wernimont AK]]
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[[Category: Wernimont, A K]]
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[[Category: Atp binding]]
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[[Category: Phosphorylation]]
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[[Category: Rossmann fold]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum

PDB ID 3tlx

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