3ufm

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Current revision (10:23, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3ufm' size='340' side='right'caption='[[3ufm]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='3ufm' size='340' side='right'caption='[[3ufm]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ufm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UFM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ufm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans] and [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UFM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3uf7|3uf7]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DR0689, DR_0689, ung ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243230 DEIRA])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Uracil-DNA_glycosylase Uracil-DNA glycosylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.27 3.2.2.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ufm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ufm OCA], [https://pdbe.org/3ufm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ufm RCSB], [https://www.ebi.ac.uk/pdbsum/3ufm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ufm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ufm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ufm OCA], [https://pdbe.org/3ufm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ufm RCSB], [https://www.ebi.ac.uk/pdbsum/3ufm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ufm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/UNG_DEIRA UNG_DEIRA]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity). [[https://www.uniprot.org/uniprot/SSB_DEIRA SSB_DEIRA]] This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair (By similarity).
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[https://www.uniprot.org/uniprot/UNG_DEIRA UNG_DEIRA] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Deira]]
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[[Category: Deinococcus radiodurans]]
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[[Category: Deinococcus radiodurans R1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Uracil-DNA glycosylase]]
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[[Category: George NP]]
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[[Category: George, N P]]
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[[Category: Keck JL]]
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[[Category: Keck, J L]]
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[[Category: Base excision repair]]
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[[Category: Glycosylase]]
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[[Category: Hydrolase]]
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[[Category: Ssb c-terminal]]
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Current revision

Co-crystal structure of Deinococcus radiodurans uracil-DNA glycosylase and the C-terminus of the single-stranded DNA-binding protein

PDB ID 3ufm

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