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3uor

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Current revision (10:25, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3uor' size='340' side='right'caption='[[3uor]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3uor' size='340' side='right'caption='[[3uor]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3uor]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanac Xanac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UOR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3uor]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_citri_pv._citri_str._306 Xanthomonas citri pv. citri str. 306]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UOR FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">malE, XAC2310 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=190486 XANAC])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.202&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uor OCA], [https://pdbe.org/3uor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uor RCSB], [https://www.ebi.ac.uk/pdbsum/3uor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uor ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uor OCA], [https://pdbe.org/3uor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uor RCSB], [https://www.ebi.ac.uk/pdbsum/3uor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uor ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q8PK66_XANAC Q8PK66_XANAC]
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The uptake of maltose and related sugars in Gram-negative bacteria is mediated by an ABC transporter encompassing a periplasmic component (the maltose-binding protein or MalE), a pore-forming membrane protein (MalF and MalG) and a membrane-associated ATPase (MalK). In the present study, the structure determination of the apo form of the putative maltose/trehalose-binding protein (Xac-MalE) from the citrus pathogen Xanthomonas citri in space group P6522 is described. The crystals contained two protein molecules in the asymmetric unit and diffracted to 2.8 A resolution. Xac-MalE conserves the structural and functional features of sugar-binding proteins and a ligand-binding pocket with similar characteristics to eight different orthologues, including the residues for maltose and trehalose interaction. This is the first structure of a sugar-binding protein from a phytopathogenic bacterium, which is highly conserved in all species from the Xanthomonas genus.
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Structure determination of a sugar-binding protein from the phytopathogenic bacterium Xanthomonas citri.,Medrano FJ, de Souza CS, Romero A, Balan A Acta Crystallogr F Struct Biol Commun. 2014 May;70(Pt 5):564-71. doi:, 10.1107/S2053230X14006578. Epub 2014 Apr 17. PMID:24817711<ref>PMID:24817711</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3uor" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Xanac]]
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[[Category: Xanthomonas citri pv. citri str. 306]]
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[[Category: Balan, A]]
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[[Category: Balan A]]
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[[Category: Medrano, F J]]
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[[Category: Medrano FJ]]
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[[Category: Souza, C S]]
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[[Category: Souza CS]]
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[[Category: Alfa/beta protein]]
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[[Category: Maltose]]
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[[Category: Periplasmic-binding protein]]
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[[Category: Sugar binding protein]]
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Current revision

The structure of the sugar-binding protein MalE from the phytopathogen Xanthomonas citri

PDB ID 3uor

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