413d

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Current revision (10:36, 1 March 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[413d]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=373d 373d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=413D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=413D FirstGlance]. <br>
<table><tr><td colspan='2'>[[413d]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=373d 373d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=413D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=413D FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=413d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=413d OCA], [https://pdbe.org/413d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=413d RCSB], [https://www.ebi.ac.uk/pdbsum/413d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=413d ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=413d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=413d OCA], [https://pdbe.org/413d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=413d RCSB], [https://www.ebi.ac.uk/pdbsum/413d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=413d ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
 
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== Publication Abstract from PubMed ==
 
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Here we demonstrate the presence of the A'-RNA conformation using the single crystal structure of a tridecamer: r(UGAGCUUCGGCUC). The average A'-RNA conformation deduced from X-ray fiber diffraction data had only been available previously, but now the presence of the A'-RNA conformation has been found in a single crystal structure for the first time. Statistical analysis showed that the A'-RNA conformation is distinguishable from the A-RNA conformation in a plot of the major groove width against the base pair inclination angle. The major groove of the A'-RNA conformation is wide enough to accommodate a protein or peptide while that of the A-RNA conformation is too narrow to do so. The presence of the A'-RNA conformation is significant for protein-RNA interaction.
 
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A'-form RNA double helix in the single crystal structure of r(UGAGCUUCGGCUC).,Tanaka Y, Fujii S, Hiroaki H, Sakata T, Tanaka T, Uesugi S, Tomita K, Kyogoku Y Nucleic Acids Res. 1999 Feb 15;27(4):949-55. PMID:9927725<ref>PMID:9927725</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 413d" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Fujii, S]]
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[[Category: Fujii S]]
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[[Category: Hiroaki, H]]
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[[Category: Hiroaki H]]
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[[Category: Kyogoku, Y]]
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[[Category: Kyogoku Y]]
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[[Category: Sakata, T]]
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[[Category: Sakata T]]
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[[Category: Tanaka, T]]
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[[Category: Tanaka T]]
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[[Category: Tanaka, Y]]
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[[Category: Tanaka Y]]
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[[Category: Tomita, K I]]
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[[Category: Tomita K-I]]
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[[Category: Uesugi, S]]
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[[Category: Uesugi S]]
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[[Category: A'-rna]]
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[[Category: Double helix]]
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[[Category: Rna]]
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Current revision

A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)

PDB ID 413d

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