7t24

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==Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa==
==Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa==
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<StructureSection load='7t24' size='340' side='right'caption='[[7t24]]' scene=''>
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<StructureSection load='7t24' size='340' side='right'caption='[[7t24]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T24 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7t24]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T24 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t24 OCA], [https://pdbe.org/7t24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t24 RCSB], [https://www.ebi.ac.uk/pdbsum/7t24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t24 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t24 OCA], [https://pdbe.org/7t24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t24 RCSB], [https://www.ebi.ac.uk/pdbsum/7t24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t24 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PUR8_PSEAE PUR8_PSEAE] Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.[UniProtKB:P0AB89]
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==See Also==
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*[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]

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Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa

PDB ID 7t24

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