8axd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human serotonin 5-HT3A receptor (apo, resting conformation)== | |
| - | + | <StructureSection load='8axd' size='340' side='right'caption='[[8axd]], [[Resolution|resolution]] 2.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8axd]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AXD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.98Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | [[Category: Lopez-Sanchez | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8axd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8axd OCA], [https://pdbe.org/8axd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8axd RCSB], [https://www.ebi.ac.uk/pdbsum/8axd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8axd ProSAT]</span></td></tr> |
| - | [[Category: Nury | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/5HT3A_HUMAN 5HT3A_HUMAN] Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.<ref>PMID:10521471</ref> <ref>PMID:12867984</ref> <ref>PMID:17392525</ref> <ref>PMID:9950429</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lopez-Sanchez U]] | ||
| + | [[Category: Nury H]] | ||
Revision as of 12:02, 6 March 2024
Human serotonin 5-HT3A receptor (apo, resting conformation)
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