8g9s
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications== | |
| - | + | <StructureSection load='8g9s' size='340' side='right'caption='[[8g9s]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8g9s]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_lactamica Neisseria lactamica] and [https://en.wikipedia.org/wiki/Rhodobacter_phage_RcNL1 Rhodobacter phage RcNL1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G9S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g9s OCA], [https://pdbe.org/8g9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g9s RCSB], [https://www.ebi.ac.uk/pdbsum/8g9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g9s ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D0W8X4_NEILA D0W8X4_NEILA] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).[PIRNR:PIRNR029950] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Neisseria lactamica]] | ||
| + | [[Category: Rhodobacter phage RcNL1]] | ||
| + | [[Category: Hu C]] | ||
| + | [[Category: Ke A]] | ||
| + | [[Category: Nam KH]] | ||
Revision as of 12:03, 6 March 2024
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
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