8r07

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'''Unreleased structure'''
 
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The entry 8r07 is ON HOLD until Paper Publication
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==C-terminal Rel-homology Domain of NFAT1==
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<StructureSection load='8r07' size='340' side='right'caption='[[8r07]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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Authors: Zak, K.M., Boettcher, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8r07]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R07 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R07 FirstGlance]. <br>
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Description: C-terminal Rel-homology Domain of NFAT1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r07 OCA], [https://pdbe.org/8r07 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r07 RCSB], [https://www.ebi.ac.uk/pdbsum/8r07 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r07 ProSAT]</span></td></tr>
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[[Category: Zak, K.M]]
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</table>
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[[Category: Boettcher, J]]
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== Function ==
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[https://www.uniprot.org/uniprot/NFAC2_HUMAN NFAC2_HUMAN] Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.<ref>PMID:21871017</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Boettcher J]]
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[[Category: Zak KM]]

Revision as of 12:08, 6 March 2024

C-terminal Rel-homology Domain of NFAT1

PDB ID 8r07

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