1qqt

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[[Image:1qqt.gif|left|200px]]
[[Image:1qqt.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1qqt |SIZE=350|CAPTION= <scene name='initialview01'>1qqt</scene>, resolution 2.03&Aring;
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The line below this paragraph, containing "STRUCTURE_1qqt", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1qqt| PDB=1qqt | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qqt OCA], [http://www.ebi.ac.uk/pdbsum/1qqt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qqt RCSB]</span>
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}}
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'''METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI'''
'''METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI'''
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[[Category: Yokoyama, S.]]
[[Category: Yokoyama, S.]]
[[Category: Zelwer, C.]]
[[Category: Zelwer, C.]]
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[[Category: helix bundle]]
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[[Category: Helix bundle]]
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[[Category: rossmann fold]]
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[[Category: Rossmann fold]]
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[[Category: trna ligase]]
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[[Category: Trna ligase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:35:55 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:17:43 2008''
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Revision as of 03:35, 3 May 2008

Image:1qqt.gif

Template:STRUCTURE 1qqt

METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI


Overview

The 3D structure of monomeric C-truncated Escherichia coli methionyl-tRNA synthetase, a class 1 aminoacyl-tRNA synthetase, has been solved at 2.0 A resolution. Remarkably, the polypeptide connecting the two halves of the Rossmann fold exposes two identical knuckles related by a 2-fold axis but with zinc in the distal knuckle only. Examination of available MetRS orthologs reveals four classes according to the number and zinc content of the putative knuckles. Extreme cases are exemplified by the MetRS of eucaryotic or archaeal origin, where two knuckles and two metal ions are expected, and by the mitochondrial enzymes, which are predicted to have one knuckle without metal ion.

About this Structure

1QQT is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features., Mechulam Y, Schmitt E, Maveyraud L, Zelwer C, Nureki O, Yokoyama S, Konno M, Blanquet S, J Mol Biol. 1999 Dec 17;294(5):1287-97. PMID:10600385 Page seeded by OCA on Sat May 3 06:35:55 2008

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OCA

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