1qrr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1qrr.gif|left|200px]]
[[Image:1qrr.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1qrr |SIZE=350|CAPTION= <scene name='initialview01'>1qrr</scene>, resolution 1.6&Aring;
+
The line below this paragraph, containing "STRUCTURE_1qrr", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UPG:URIDINE-5&#39;-DIPHOSPHATE-GLUCOSE'>UPG</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1qrr| PDB=1qrr | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qrr OCA], [http://www.ebi.ac.uk/pdbsum/1qrr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qrr RCSB]</span>
+
-
}}
+
'''CRYSTAL STRUCTURE OF SQD1 PROTEIN COMPLEX WITH NAD AND UDP-GLUCOSE'''
'''CRYSTAL STRUCTURE OF SQD1 PROTEIN COMPLEX WITH NAD AND UDP-GLUCOSE'''
Line 30: Line 27:
[[Category: Mulichak, A M.]]
[[Category: Mulichak, A M.]]
[[Category: Theisen, M J.]]
[[Category: Theisen, M J.]]
-
[[Category: rossmann fold]]
+
[[Category: Rossmann fold]]
-
[[Category: sdr homolog]]
+
[[Category: Sdr homolog]]
-
[[Category: short hydrogen bond]]
+
[[Category: Short hydrogen bond]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:37:49 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:18:04 2008''
+

Revision as of 03:37, 3 May 2008

Image:1qrr.gif

Template:STRUCTURE 1qrr

CRYSTAL STRUCTURE OF SQD1 PROTEIN COMPLEX WITH NAD AND UDP-GLUCOSE


Overview

The SQD1 enzyme is believed to be involved in the biosynthesis of the sulfoquinovosyl headgroup of plant sulfolipids, catalyzing the transfer of SO(3)(-) to UDP-glucose. We have determined the structure of the complex of SQD1 from Arabidopsis thaliana with NAD(+) and the putative substrate UDP-glucose at 1.6-A resolution. Both bound ligands are completely buried within the binding cleft, along with an internal solvent cavity which is the likely binding site for the, as yet, unidentified sulfur-donor substrate. SQD1 is a member of the short-chain dehydrogenase/reductase (SDR) family of enzymes, and its structure shows a conservation of the SDR catalytic residues. Among several highly conserved catalytic residues, Thr-145 forms unusually short hydrogen bonds with both susceptible hydroxyls of UDP-glucose. A His side chain may also be catalytically important in the sulfonation.

About this Structure

1QRR is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

Crystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovose., Mulichak AM, Theisen MJ, Essigmann B, Benning C, Garavito RM, Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13097-102. PMID:10557279 Page seeded by OCA on Sat May 3 06:37:49 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qrr"
Personal tools