6vs4

<table><tr><td colspan='2'>[[6vs4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VS4 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vs4 OCA], [http://pdbe.org/6vs4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vs4 RCSB], [http://www.ebi.ac.uk/pdbsum/6vs4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vs4 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/SAR1_ENCCU SAR1_ENCCU]] Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).

[[Category: Structural genomic]]

[[Category: Adp ribosylation factor-like gtp binding protein]]

[[Category: Copii coat gtpase sar1]]

[[Category: Hydrolase]]

[[Category: Ssgcid]]