6vvz

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Current revision (14:40, 6 March 2024) (edit) (undo)
 
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====
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==Mycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with Sorangicin==
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<StructureSection load='6vvz' size='340' side='right'caption='[[6vvz]]' scene=''>
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<StructureSection load='6vvz' size='340' side='right'caption='[[6vvz]], [[Resolution|resolution]] 3.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6vvz]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VVZ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6vvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vvz OCA], [http://pdbe.org/6vvz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vvz RCSB], [http://www.ebi.ac.uk/pdbsum/6vvz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vvz ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.72&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SRN:SORANGICIN+A'>SRN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vvz OCA], [https://pdbe.org/6vvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vvz RCSB], [https://www.ebi.ac.uk/pdbsum/6vvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vvz ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPOA_MYCTU RPOA_MYCTU] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00059]<ref>PMID:22570422</ref>
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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*[[Sigma factor 3D structures|Sigma factor 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Boyaci H]]
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[[Category: Campbell EA]]
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[[Category: Chen J]]
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[[Category: Darst SA]]
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[[Category: Lilic M]]

Current revision

Mycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with Sorangicin

PDB ID 6vvz

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