7jt3

==Rotated 70S ribosome stalled on long mRNA with ArfB-1 and ArfB-2 bound in the A site (+9-IV)==

<StructureSection load='7jt3' size='340' side='right'caption='[[7jt3]], [[Resolution|resolution]] 3.70&Aring;' scene=''>

<table><tr><td colspan='2'>[[7jt3]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JT3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JT3 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jt3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jt3 OCA], [https://pdbe.org/7jt3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jt3 RCSB], [https://www.ebi.ac.uk/pdbsum/7jt3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jt3 ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/RL2_ECOLI RL2_ECOLI] One of the primary rRNA binding proteins. Located near the base of the L1 stalk, it is probably also mobile. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is highly controversial.[HAMAP-Rule:MF_01320_B] In the E.coli 70S ribosome in the initiation state it has been modeled to make several contacts with the 16S rRNA (forming bridge B7b, PubMed:12809609); these contacts are broken in the model with bound EF-G.[HAMAP-Rule:MF_01320_B]

==See Also==

*[[Ribosome 3D structures|Ribosome 3D structures]]

[[Category: Escherichia coli K-12]]

[[Category: Carbone CE]]

[[Category: Korostelev AA]]