7kdt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "7kdt" [edit=sysop:move=sysop])
Current revision (14:56, 6 March 2024) (edit) (undo)
 
Line 1: Line 1:
-
====
+
==Human Tom70 in complex with SARS CoV2 Orf9b==
-
<StructureSection load='7kdt' size='340' side='right'caption='[[7kdt]]' scene=''>
+
<StructureSection load='7kdt' size='340' side='right'caption='[[7kdt]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7kdt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KDT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KDT FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7kdt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kdt OCA], [http://pdbe.org/7kdt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7kdt RCSB], [http://www.ebi.ac.uk/pdbsum/7kdt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7kdt ProSAT]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kdt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kdt OCA], [https://pdbe.org/7kdt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kdt RCSB], [https://www.ebi.ac.uk/pdbsum/7kdt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kdt ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TOM70_HUMAN TOM70_HUMAN] Acts as receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) (PubMed:12526792). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed:12526792, PubMed:35025629). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (PubMed:20628368, PubMed:25609812, PubMed:32728199). Upon Sendai virus infection, recruits HSP90AA1:IRF3:BAX in mitochondrion and the complex induces apoptosis (PubMed:25609812).<ref>PMID:12526792</ref> <ref>PMID:20628368</ref> <ref>PMID:25609812</ref> <ref>PMID:32728199</ref> <ref>PMID:35025629</ref>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Z-disk]]
+
[[Category: Severe acute respiratory syndrome coronavirus 2]]
 +
[[Category: QCRG Structural Biology Consortium]]

Current revision

Human Tom70 in complex with SARS CoV2 Orf9b

PDB ID 7kdt

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7kdt"
Personal tools