7lum

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m (Protected "7lum" [edit=sysop:move=sysop])
Current revision (15:00, 6 March 2024) (edit) (undo)
 
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====
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==Human TRiC in ATP/AlFx closed state==
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<StructureSection load='7lum' size='340' side='right'caption='[[7lum]]' scene=''>
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<StructureSection load='7lum' size='340' side='right'caption='[[7lum]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7lum]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LUM FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lum OCA], [https://pdbe.org/7lum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lum RCSB], [https://www.ebi.ac.uk/pdbsum/7lum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lum ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lum OCA], [https://pdbe.org/7lum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lum RCSB], [https://www.ebi.ac.uk/pdbsum/7lum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lum ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Hereditary sensory and autonomic neuropathy with spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.<ref>PMID:20080638</ref>
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==See Also==
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*[[Chaperonin 3D structures|Chaperonin 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Aebersold R]]
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[[Category: Chiu W]]
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[[Category: Dermody TS]]
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[[Category: Frydman J]]
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[[Category: Gestaut D]]
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[[Category: Knowlton JJ]]
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[[Category: Leitner A]]
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[[Category: Ma B]]
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[[Category: Prasad BVV]]
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[[Category: Seven AB]]
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[[Category: Shanker S]]
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[[Category: Taylor G]]
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[[Category: Wilson GJ]]
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[[Category: Yates NA]]

Current revision

Human TRiC in ATP/AlFx closed state

PDB ID 7lum

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