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5sby
From Proteopedia
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==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with Z1878656559== | ==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with Z1878656559== | ||
| - | <StructureSection load='5sby' size='340' side='right'caption='[[5sby]]' scene=''> | + | <StructureSection load='5sby' size='340' side='right'caption='[[5sby]], [[Resolution|resolution]] 1.22Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SBY FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5sby]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SBY FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sby OCA], [https://pdbe.org/5sby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sby RCSB], [https://www.ebi.ac.uk/pdbsum/5sby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sby ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.217Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8BI:(1R,2R)-2,4,4-trimethyl-N-[(1H-pyrazol-3-yl)methyl]cyclopentan-1-amine'>8BI</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sby OCA], [https://pdbe.org/5sby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sby RCSB], [https://www.ebi.ac.uk/pdbsum/5sby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sby ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
[[Category: Bezerra GA]] | [[Category: Bezerra GA]] | ||
[[Category: Bountra C]] | [[Category: Bountra C]] | ||
Current revision
CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with Z1878656559
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