5tiq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:41, 6 March 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5tiq' size='340' side='right'caption='[[5tiq]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
<StructureSection load='5tiq' size='340' side='right'caption='[[5tiq]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5tiq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Paramecium_bursaria_chlorella_virus_1 Paramecium bursaria chlorella virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1j5q 1j5q]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TIQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TIQ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5tiq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paramecium_bursaria_Chlorella_virus_1 Paramecium bursaria Chlorella virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1j5q 1j5q]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TIQ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7CV:6-deoxy-2,3-di-O-methyl-alpha-L-mannopyranose'>7CV</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=RM4:6-DEOXY-BETA-L-MANNOPYRANOSE'>RM4</scene>, <scene name='pdbligand=XXR:6-DEOXY-ALPHA-D-MANNOPYRANOSE'>XXR</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.537&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j5q|1j5q]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7CV:6-deoxy-2,3-di-O-methyl-alpha-L-mannopyranose'>7CV</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=RM4:6-DEOXY-BETA-L-MANNOPYRANOSE'>RM4</scene>, <scene name='pdbligand=XXR:6-DEOXY-ALPHA-D-MANNOPYRANOSE'>XXR</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tiq OCA], [http://pdbe.org/5tiq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tiq RCSB], [http://www.ebi.ac.uk/pdbsum/5tiq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tiq ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tiq OCA], [https://pdbe.org/5tiq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tiq RCSB], [https://www.ebi.ac.uk/pdbsum/5tiq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tiq ProSAT]</span></td></tr>
</table>
</table>
-
<div style="background-color:#fffaf0;">
+
== Function ==
-
== Publication Abstract from PubMed ==
+
[https://www.uniprot.org/uniprot/MCP_PBCV1 MCP_PBCV1]
-
The glycans of the major capsid protein (Vp54) of Paramecium bursaria chlorella virus (PBCV-1) were recently described and found to be unusual. This prompted a reexamination of the previously reported Vp54 X-ray structure. A detailed description of the complete glycoprotein was achieved by combining crystallographic data with molecular modeling. The crystallographic data identified most of the monosaccharides located close to the protein backbone, but failed to detect those further from the glycosylation sites. Molecular modeling complemented this model by adding the missing monosaccharides and examined the conformational preference of the whole molecule, alone or within the crystallographic environment. Thus, combining X-ray crystallography with carbohydrate molecular modeling resulted in determining the complete glycosylated structure of a glycoprotein. In this case, it is the chlorovirus PBCV-1 major capsid protein.
+
-
 
+
-
Structure of the chlorovirus PBCV-1 major capsid glycoprotein determined by combining crystallographic and carbohydrate molecular modeling approaches.,De Castro C, Klose T, Speciale I, Lanzetta R, Molinaro A, Van Etten JL, Rossmann MG Proc Natl Acad Sci U S A. 2017 Dec 18. pii: 1613432115. doi:, 10.1073/pnas.1613432115. PMID:29255015<ref>PMID:29255015</ref>
+
-
 
+
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
-
<div class="pdbe-citations 5tiq" style="background-color:#fffaf0;"></div>
+
==See Also==
==See Also==
-
*[[Virus coat protein|Virus coat protein]]
+
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
-
== References ==
+
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Paramecium bursaria chlorella virus 1]]
+
[[Category: Paramecium bursaria Chlorella virus 1]]
-
[[Category: Castro, C De]]
+
[[Category: De Castro C]]
-
[[Category: Etten, J L.Van]]
+
[[Category: Klose T]]
-
[[Category: Klose, T]]
+
[[Category: Molinaro A]]
-
[[Category: Molinaro, A]]
+
[[Category: Rossmann MG]]
-
[[Category: Rossmann, M G]]
+
[[Category: Speciale I]]
-
[[Category: Speciale, I]]
+
[[Category: Van Etten JL]]
-
[[Category: Viral protein]]
+

Current revision

The Structure of the Major Capsid protein of PBCV-1

PDB ID 5tiq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5tiq"
Personal tools