1qv0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1qv0.jpg|left|200px]]
[[Image:1qv0.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1qv0 |SIZE=350|CAPTION= <scene name='initialview01'>1qv0</scene>, resolution 1.10&Aring;
+
The line below this paragraph, containing "STRUCTURE_1qv0", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=CZH:C2-HYDROPEROXY-COELENTERAZINE'>CZH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Renilla-luciferin_2-monooxygenase Renilla-luciferin 2-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.12.5 1.13.12.5] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1qv0| PDB=1qv0 | SCENE= }}
-
|RELATEDENTRY=[[1el4|1EL4]], [[1ej3|1EJ3]], [[1jf0|1JF0]], [[1jf2|1JF2]], [[1qv1|1QV1]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qv0 OCA], [http://www.ebi.ac.uk/pdbsum/1qv0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qv0 RCSB]</span>
+
-
}}
+
'''Atomic resolution structure of obelin from Obelia longissima'''
'''Atomic resolution structure of obelin from Obelia longissima'''
Line 32: Line 29:
[[Category: Vysotski, E S.]]
[[Category: Vysotski, E S.]]
[[Category: Wang, B C.]]
[[Category: Wang, B C.]]
-
[[Category: atomic resolution]]
+
[[Category: Atomic resolution]]
-
[[Category: bioluminescence]]
+
[[Category: Bioluminescence]]
-
[[Category: calcium binding]]
+
[[Category: Calcium binding]]
-
[[Category: crystal structure]]
+
[[Category: Crystal structure]]
-
[[Category: ef-hand]]
+
[[Category: Ef-hand]]
-
[[Category: obelin]]
+
[[Category: Obelin]]
-
[[Category: photoprotein]]
+
[[Category: Photoprotein]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:44:08 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:19:25 2008''
+

Revision as of 03:44, 3 May 2008

Image:1qv0.jpg

Template:STRUCTURE 1qv0

Atomic resolution structure of obelin from Obelia longissima


Overview

The spatial structure of the Ca(2+)-regulated photoprotein obelin has been solved to resolution of 1.1A. Two oxygen atoms are revealed substituted at the C2-position of the coelenterazine in contrast to the obelin structure at 1.73A resolution where one oxygen atom only was disclosed. The electron density of the second oxygen atom was very weak but after exposing the crystals to a trace of Ca(2+), the electron densities of both oxygen atoms became equally intense. In addition, one Ca(2+) was found bound in the loop of the first EF-hand motif. Four of the ligands were provided by protein residues Asp30, Asn32, Asn34, and the main chain oxygen of Lys36. The other two were from water molecules. From a comparison of B-factors for the residues constituting the active site, it is suggested that the variable electron densities observed in various photoprotein structures could be attributed to different mobilities of the peroxy oxygen atoms.

About this Structure

1QV0 is a Single protein structure of sequence from Obelia longissima. Full crystallographic information is available from OCA.

Reference

Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine., Liu ZJ, Vysotski ES, Deng L, Lee J, Rose J, Wang BC, Biochem Biophys Res Commun. 2003 Nov 14;311(2):433-9. PMID:14592432 Page seeded by OCA on Sat May 3 06:44:08 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qv0"
Personal tools