8tum

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'''Unreleased structure'''
 
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The entry 8tum is ON HOLD until Paper Publication
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==Type IV pilus from Pseudomonas PAO1 strain==
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<StructureSection load='8tum' size='340' side='right'caption='[[8tum]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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Authors: Thongchol, J., Zhang, J., Zeng, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8tum]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TUM FirstGlance]. <br>
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Description: Type IV pilus from Pseudomonas PAO1 strain
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tum OCA], [https://pdbe.org/8tum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tum RCSB], [https://www.ebi.ac.uk/pdbsum/8tum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tum ProSAT]</span></td></tr>
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[[Category: Thongchol, J]]
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</table>
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[[Category: Zeng, L]]
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== Function ==
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[[Category: Zhang, J]]
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[https://www.uniprot.org/uniprot/PILA_PSEAE PILA_PSEAE] Major component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility facilitated by cycles of extension, adhesion, and retraction of T4P fibers (PubMed:9282737, PubMed:26041805, PubMed:31431558). In addition, plays a critical role in type II secretion of exoenzymes by interacting with specific components such as XcpT or XcpU (PubMed:9282737). Modulates host calcium signaling through interaction with host calcium-modulating cyclophilin ligand (PubMed:23266901).<ref>PMID:23266901</ref> <ref>PMID:26041805</ref> <ref>PMID:31431558</ref> <ref>PMID:9282737</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Thongchol J]]
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[[Category: Zeng L]]
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[[Category: Zhang J]]

Revision as of 13:18, 13 March 2024

Type IV pilus from Pseudomonas PAO1 strain

PDB ID 8tum

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