8yhi

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m (Protected "8yhi" [edit=sysop:move=sysop])
Current revision (13:21, 13 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8yhi is ON HOLD
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==The Crystal Structure of SHP1 from Biortus.==
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<StructureSection load='8yhi' size='340' side='right'caption='[[8yhi]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8yhi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YHI FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yhi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yhi OCA], [https://pdbe.org/8yhi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yhi RCSB], [https://www.ebi.ac.uk/pdbsum/8yhi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yhi ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PTN6_HUMAN PTN6_HUMAN] Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.<ref>PMID:11266449</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cheng W]]
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[[Category: Qi J]]
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[[Category: Shen Z]]
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[[Category: Wang F]]
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[[Category: Yuan Z]]

Current revision

The Crystal Structure of SHP1 from Biortus.

PDB ID 8yhi

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