1wv2
From Proteopedia
(Difference between revisions)
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==Crystal structure of thiamine biosynthesis protein from Pseudomonas Aeruginosa== | ==Crystal structure of thiamine biosynthesis protein from Pseudomonas Aeruginosa== | ||
- | <StructureSection load='1wv2' size='340' side='right'caption='[[1wv2]]' scene=''> | + | <StructureSection load='1wv2' size='340' side='right'caption='[[1wv2]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WV2 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[1wv2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WV2 FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wv2 OCA], [https://pdbe.org/1wv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wv2 RCSB], [https://www.ebi.ac.uk/pdbsum/1wv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wv2 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1wv2 TOPSAN]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wv2 OCA], [https://pdbe.org/1wv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wv2 RCSB], [https://www.ebi.ac.uk/pdbsum/1wv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wv2 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1wv2 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/THIG_PSEAE THIG_PSEAE] Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
+ | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Almo SC]] | [[Category: Almo SC]] | ||
[[Category: Burley SK]] | [[Category: Burley SK]] | ||
[[Category: Fedorov AA]] | [[Category: Fedorov AA]] | ||
[[Category: Fedorov EV]] | [[Category: Fedorov EV]] |
Current revision
Crystal structure of thiamine biosynthesis protein from Pseudomonas Aeruginosa
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